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© 1976 British Society for Rheumatology

other

OCCULT GASTROINTESTINAL BLEEDING DUE TO ASPIRIN: COMPARISON OF TWO COMPOUNDS

J. E. ROSSOUW, M. DAVIS, M. CLARKE and ROGER WILLIAMS

Liver Unit and King's College Hospital Medical School Denmark Hill, London, SE5 8RX

Occult gastrointestinal bleeding as measured by the faecal 51Cr-labelled red-cell loss was compared in eight healthy volunteers while on therapeutic doses of soluble aspirin and a new slow-release formulation of aspirin (Deskoval).

While both preparations led to increased faecal blood loss, this was significantly less during administration of Deskoval than when soluble aspirin was taken.


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