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© 1976 British Society for Rheumatology


other

SULINDAC IN OSTEOARTHROSIS OF THE HIP

P. A. DIEPPE, H. C. BURRY, R. GRAHAME and T. PERERA

Guy's Arthritis Research Unit, Guy's Hospital Medical School London SE1 9RT

Correspondence to: Requests for reprints to Dr. P. A. Dieppe, Department of Experimental Pathology and Rheumatology, St. Bartholomew's Hospital, London EC1A 7BE.

Sulindac (400 mg/day) has been compared with ibuprofen (1200 mg/day) in 40 patients with osteoarthrosis of the hip, over an eight-week period, in a double-blind controlled clinical trial. The two drugs were comparable in terms of patient preference, effects on hip movements, and toxicity. Sulindac showed superior analgesic properties to ibuprofen, resulting in a significantly greater reduction in pain on weight-bearing and with passive movements P<0.01).


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