© 1976 British Society for Rheumatology
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SULINDAC IN OSTEOARTHROSIS OF THE HIP
Guy's Arthritis Research Unit, Guy's Hospital Medical School London SE1 9RT
Correspondence to:
Requests for reprints to Dr. P. A. Dieppe, Department of Experimental Pathology and Rheumatology, St. Bartholomew's Hospital, London EC1A 7BE.
Sulindac (400 mg/day) has been compared with ibuprofen (1200 mg/day) in 40 patients with osteoarthrosis of the hip, over an eight-week period, in a double-blind controlled clinical trial. The two drugs were comparable in terms of patient preference, effects on hip movements, and toxicity. Sulindac showed superior analgesic properties to ibuprofen, resulting in a significantly greater reduction in pain on weight-bearing and with passive movements P<0.01).