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© 1976 British Society for Rheumatology

other

PROGRESSIVE DESTRUCTION OF THE FEMORAL HEAD IN THE ASSOCIATION WITH FAMILIAL HYPERCHOLESTEROLAEMIA

C. MURRAY-LESLIE, Senior Registrar, M. MAGARO, Research Fellow{dagger} and V. WRIGHT, Professor of Rheumatology.

{dagger}Catholic University Rome

Correspondence to: Reprint requests to Dr. C. Murray-Leslie, Rheumatism Research Unit, 36 Clarendon Road, Leeds LS2 9NL.

The case history of a 47-year-old woman is described who presented with a rapidly progressive destructivearthritis of both femoral heads, similar to that seen with avascular necrosis and who was discovered in addition to have familial hypercholesterolaemia associated with tendon xanthomata. Details of the family are presented and the relevant literature on the association between hypercholesterolaemia and bone and joint lesions is reviewed. As far as the authors are aware, no other case of this type has been previously reported.


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