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© 1978 British Society for Rheumatology

research-article

COPPER—AN INDEX OF EROSIVE ACTIVITY?*

A. G. WHITE, P. SCUDDER, T. L. DORMANDY and V. M. MARTIN

Department of Rheumatology and Department of Chemical pathology Whittington Hospital, London N19 3UA

Correspondence to: Requests for reprints to: Dr. A. 0. White

Using atomic absorption spectrophotometry the copper content of synovial fluid has been compared in rheumatoid and osteoarthrotic synovial fluids. Synovial fluid caeruloplasmin has been determined by single radial immunodiffusion. Both are significantly increased in the rheumatoid group. Serum Copper, similarly estimated, shows a trend to greater elevation with increasing degree of rheumatoid erosion as assessed radiologically.

Paper read at the Annual Meeting of the British Association for Rheumatology and Rehabilitation, London April 1977.


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