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© 1981 British Society for Rheumatology

research-article

ARTERITIS ASSOCIATED WITH HYPER VISCOSITY-LIKE SYNDROME IN RHEUMATOID ARTHRITIS, TREATED BY INTERMITTENT PLASMA-EXCHANGE FOR 2.5 YEARS

J. DEQUEKER, M. WALRAVENS, A. LEYS and R. PIETERS

Rheumatology and Ophtalmology Unit, Katholieke Universiteit Leuven 3000 Leuven, Belgium

Correspondence to: Requests for reprints to Prof. Dr. J. Dequeker, Afdeling Reumatologie, Academische Ziekenhuizen, Katholieke Universiteit Leuven, 300 Leuven, Belgium.

A case is reported of a hyperviscosity-like syndrome in a 53-year-old male suffering from rheumatoid arthritis. The clinical presentation was an acute abdomen, peripheral neuritis, otovestibular areflexy, and central retinal vein thrombosis (papilloedema and retinopathy with venous engorgement, haemorrhages and exudates). Plasma viscosity was normal and whole blood viscosity, measured with an Oswald viscometer, was slightly elevated. The patient had markedly elevated rheumatoid factor titre and fibrinogen level. Histologically, there were no signs of arteritis in the mesentery.

Intermittent plasma-exchange resulted in general improvement and no new vascular accidents after 2.5 years.


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