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© 1982 British Society for Rheumatology

research-article

MULTISYSTEM PRESENTATIONOF EOSINOPHILIC FASCIITIS

D. CASPI1, R. FISHEL1, M. VARON3, E. YONA3, M. BARATZ2 and M. YARON1

1Department of Rheumatology Ichilov Hospital, Tel Aviv Medical Center and the Sackler Scholl of Medicine, Tel Aviv University Tel Aviv 64239
2Department of Pathology, Ichilov Hospital, Tel Aviv Medical Center and the Sackler Scholl of Medicine, Tel Aviv University Tel Aviv 64239
3Department of Internal Medicine, Assaf Harofe Hospital Zerifin, Israel

Correspondence to: Requests for reprints to Dr. M. Yaron

A 20-year-old man experienced the onset of progressive scleroderma-like skin changes with eosinophilia and hypergammaglobulinaemia after strenuous military activity. A biopsy showed fasciitis. Conconmitant splenmegaly, polysynovitis, restrictive lung function, myositis, decreased hepatic cloting factors and proteinuria were documented. He responded well to corticosteroids, relapsed upon their discontinuation and had a complete remission of both skin and systemic features while on penicillamine and azathioprine. He is now in good health and has received no medication for the past two years.


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