© 1982 British Society for Rheumatology
research-article |
TOXIC EPIDERMAL NECROLYSIS IN A PATIENT TREATED WITH GOLD SLTS AND BENOXAPROFEN
1Department of Rheumatology Ealing Hospital Southall, Middlesex UB1 3HW
2Histopathology, Ealing Hospital Southall, Middlesex UB1 3HW
3Rheumatology Unit, Hammersmith Hospital London W12 0HS
Correspondence to:
Requests for reprints to Dr. C. Feldman.
Fatal toxic epdiermal necrolyis is described in a patient, trated concurrently with sodium aurothiomalate and benoxaprofen, who had previously had these two drugs separately, with only minor mucocutaneous problems while on gold, and no adverse effects from benoxaprofen.
It is suggested that benoxaprofen could act synergistically with gold, resulting in enhancement of mucocutaneous side-effects, which are common to both these drugs.