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© 1982 British Society for Rheumatology

research-article

A DOUBLE-BLIND COMPARATIVE STUDY OF METRONIDAZOLE AND PLACEBO IN RHEUMATOID ARTHRITIS

J. A. L. HARKNESS*, A. J. GRIFFIN, I. HEINRICH, T. GIBSON and R. GRAHAME

Department of Rheumatology, Guy's Hospital London SE1 9RT

Correspondence to: Requests for reprints to Dr. R. Grahame.

Twenty patients with active rheumatoid arthritis participated in a six-week placebo-controlled trial of metronidazole. No significant differences were observed in clinical and laboratory parameters between the metronidazole and placebo groups at the completion of the study.

*Present address: Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, BathBAl 1RL.


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