© 1984 British Society for Rheumatology
research-article |
PSORIATIC ARTHRITIS IN PSORIATIC PATIENTS
1Rheumatological Unit of the University Naples, Italy
2Dermatological Unit of the Health Unit 42 of Regione Campania Naples, Italy
Correspondence to:
Address correspondence to Dr. Raffaele Scarpa, Department of Internal Medicine and Rheumatology, 2 Facolta di Medicina e Chirurgia, Via S. Pansini 5,80131. Napoli, Italy.
One hundred and eighty patients with psoriasis have been studied in the Neapolitan area to find the prevalence of arthritis in psoriasis. Wright and Moll's criteria for the diagnosis of arthritis were applied. Of 180 psoriatic patients, 62 exhibited arthritis (34.4% of total cases) According to Moll and Wright's five broad clinical forms of arthritis, the following distribution was found: poly-articular in 38.7% of arthritic patients, mono-oligoarticular in 16.1%, distal interphalangeal in 7.5%, deforming or mutilans in 2.3% and spondylitic and/or sacro-iliitic in 20.9%. In 14.5% of arthritic patients an overlap of the spondylitic form and peripheral involvement was also found. Stratification by age of patient populations shows that cutaneous pathology has a homogeneous distribution in the various age decades, while joint symptoms are seen maximally in the sixth decade and are absent in the first two decades. The relationship between the onset of skin lesions and joint pathology demonstrates that skin lesions preceded arthritis in 64.5% of the cases, whilst arthritis antedated psoriasis in only 19.35%. In 16.1% of cases psoriasis and arthritis began almost simultaneously. Nail changes were present in 63percnt; of arthritic patients and in 37% of psoriatic subjects without arthritis. Furthermore, in 88% of arthritic patients in whom arthritis preceded skin lesions, nail changes antedated the onset of clinically apparent psoriasis. Extra-articular features were not found. This absence might be associated with the usual seronegativity for rheumatoid factor in psoriatic arthritis, also confirmed in this survey.
KEY WORDS: Psoriatic arthritis, Seronegative arthritis, Psoriasis
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  O B V Pedersen, A J Svendsen, L Ejstrup, A Skytthe, and P Junker The occurrence of psoriatic arthritis in Denmark Ann Rheum Dis, October 1, 2008; 67(10): 1422 - 1426. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O B Pedersen, A J Svendsen, L Ejstrup, A Skytthe, and P Junker On the heritability of psoriatic arthritis. Disease concordance among monozygotic and dizygotic twins Ann Rheum Dis, October 1, 2008; 67(10): 1417 - 1421. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P Gisondi, I Tinazzi, G El-Dalati, M Gallo, D Biasi, L M Barbara, and G Girolomoni Lower limb enthesopathy in patients with psoriasis without clinical signs of arthropathy: a hospital-based case-control study Ann Rheum Dis, January 1, 2008; 67(1): 26 - 30. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Y P C Ho, A. Barton, J. Worthington, W. Thomson, A. J Silman, and I. N Bruce HLA-Cw6 and HLA-DRB1*07 together are associated with less severe joint disease in psoriatic arthritis Ann Rheum Dis, June 1, 2007; 66(6): 807 - 811. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D D Gladman, C Antoni, P Mease, D O Clegg, and P Nash Psoriatic arthritis: epidemiology, clinical features, course, and outcome Ann Rheum Dis, March 1, 2005; 64(suppl_2): ii14 - ii17. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P Mease TNF{alpha} therapy in psoriatic arthritis and psoriasis Ann Rheum Dis, July 1, 2004; 63(7): 755 - 758. [Full Text] [PDF]
|
|
|
|
 |
|
 L. Williamson, N. Dalbeth, J. L. Dockerty, B. C. Gee, R. Weatherall, and B. P. Wordsworth Extended report: nail disease in psoriatic arthritis--clinically important, potentially treatable and often overlooked Rheumatology, June 1, 2004; 43(6): 790 - 794. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Kane, L. Stafford, B. Bresnihan, and O. FitzGerald A classification study of clinical subsets in an inception cohort of early psoriatic peripheral arthritis--'DIP or not DIP revisited' Rheumatology, December 1, 2003; 42(12): 1469 - 1476. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Kane, L. Stafford, B. Bresnihan, and O. FitzGerald A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience Rheumatology, December 1, 2003; 42(12): 1460 - 1468. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P J Mease Tumour necrosis factor (TNF) in psoriatic arthritis: pathophysiology and treatment with TNF inhibitors Ann Rheum Dis, April 1, 2002; 61(4): 298 - 304. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P J Mease Cytokine blockers in psoriatic arthritis Ann Rheum Dis, November 1, 2001; 60(90003): iii37 - 40. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Girolomoni and D. Abeni Anti-Tumor Necrosis Factor {alpha} Therapy in Psoriatic Arthritis and Psoriasis Arch Dermatol, June 1, 2001; 137(6): 784 - 785. [Full Text] [PDF]
|
|
|
|
|
|
B Månsson, A Gülfe, P Geborek, D Heinegård, and T Saxne Release of cartilage and bone macromolecules into synovial fluid: differences between psoriatic arthritis and rheumatoid arthritis Ann Rheum Dis, January 1, 2001; 60(1): 27 - 31. [Abstract] [Full Text]
|
|
|
|
 |
|
 I. A. TRAIL and J. K. STANLEY The Hand in Psoriasis J Hand Surg Eur Vol., February 1, 1990; 15(1): 79 - 83. [Abstract] [PDF]
|
|