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© 1985 British Society for Rheumatology

case-report

FENCLOFENAC-INDUCED SELECTIVE IGA DEFICIENCY IN RHEUMATOID ARTHRITIS

M. FARR, G. R. STRUTHERS, D. G. I. SCOTT and P. A. BACON

Department of Rheumatology, University of Birmingham, The Medical School Birmingham BIS 2TJ, UK

Correspondence to: Address correspondence to Dr. Margaret Farr.

A 35-year-old man with seropositive rheumatoid arthritis developed selective IgA deficiency during treatment with fenclofenac. His arthritis remained quiescent while taking the drug and following its withdrawal his condition relapsed and his serum IgA level returned to normal. This case demonstrates the association of selective IgA deficiency with remission in rheumatoid arthritis induced by fenclofenac as well as aurothiomalate and sulphasalazine. It also shows severe relapse after withdrawal of fenclofenac.

KEY WORDS: Rheumatoid arthritis, Selective IgA deficiency, Fenclofenac


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