Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by UPADHYAY, R.
Right arrow Articles by RUSSELL, R. I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by UPADHYAY, R.
Right arrow Articles by RUSSELL, R. I.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1988 British Society for Rheumatology

brief-report

CAMPYLOBACTER PYLORI ASSOCIATED GASTRITIS IN PATIENTS WITH RHEUMATOID ARTHRITIS TAKING NONSTEROIDAL ANTI-INFLAMMATORY DRUGS

R. UPADHYAY1,4, A. HOWATSON2, A. McKINLAY1, B. J. Z. DANESH1, R. D. STURROCK3 and R. I. RUSSELL1

1Gastroenterology Unit Royal Infirmary, Glasgow G31 2ER, UK
2Department of Pathology Royal Infirmary, Glasgow G31 2ER, UK
3Centre for Rheumatic Diseases Royal Infirmary, Glasgow G31 2ER, UK

Correspondence to: 4Address correspondence to Dr. R. Upadhyay

Fifty-two patients with rheumatoid arthritis taking nonsteroidal anti-inflammatory drugs were studied in order to assess the carriage rate of Campylobacterpylori (C. pylori) with reference to dyspeptic symptoms, endoscopic appearance and antral histology. All patients were interviewed using a standard gastrointestinal symptom scoring questionnaire and underwent endoscopy at which two antral biopsies were obtained. Sections were examined for the presence and severity of gastritis and of C. pylori.

Forty-four of 52 patients (85%) had histological evidence of gastritis. Twenty-six of 44 (59%) patients with gastritis were positive for C. pylori. Twenty-six of 28 patients with 'active' (polymorph infiltration) chronic gastritis were positive for C. pylori (p <0.002). Sixteen of 26 bacteria-positive patients had gastrointestinal symptoms compared with eight of 26 bacteria-negative patients (p < 0.05) and this may have therapeutic implications. There was no correlation between the presence of organisms and the appearances at endoscopy.

KEY WORDS: 'Active' chronic gastritis, Prevalence, Dyspepsia, Endoscopy.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Ann Rheum DisHome page
X Calvet, J Gratacos, J Font, M Larrosa, I Sanfeliu, and M Roque
Helicobacter pylori does not play a part in the dyspeptic complaints of rheumatology patients receiving long term treatment with non-steroidal anti-inflammatory drugs
Ann Rheum Dis, July 1, 2002; 61(7): 641 - 643.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.