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© 1988 British Society for Rheumatology

other

ERRORS IN THE PREDICTION OF CREATININE CLEARANCE IN PATIENTS WITH RHEUMATOID ARTHRITIS

M. BOERS1, B. A. C. DIJKMANS1, F. C. BREEDVELD1 and H. MATTIE2

1Departments of Rheumatology, Leiden University and University Hospital The Netherlands
2Departments of Infectious Diseases, Leiden University and University Hospital The Netherlands

Correspondence to: Address correspondence to M. Boers, M.D., University Hospital, Department of Rheumatology, Bldg. 1, C2-Q, PO Box 9600, 2300 RC Leiden, The Netherlands.

The accuracy of two equations used to predict creatinine clearance was assessed in 27 patients with rheumatoid arthritis (RA) and 34 controls. Both equations were accurate in controls, but overestimated the clearance in RA patients. The degree of overestimation was not related to patient characteristics. Uncritical use of these equations in RA patients may lead to serious error.

KEY WORDS: Renal function, Muscle mass


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