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© 1989 British Society for Rheumatology

research-article

MORTALITY OF JAMAICAN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

E. N. HARRIS, E. WILLIAMS, D. J. SHAH and K. DE CEULAER1

Departments of Medicine and Pathology, University of the West Indies Kingston, Jamaica

Correspondence to: 1Correspondence to: K. De Ceulaer, MRC Laboratories, University of the West Indies, Kingston 7, Jamaica.

A retrospective study of all patients with systemic lupus erythematosus (SLE) who died at the University Hospital of the West Indies over a 14-year period is presented. The major cause of death was infection followed by renal failure. Gram-negative organisms were the major microbiological agents causing infections. Side-effects of therapy were common, in particular bone marrow depression and haemorrhage related to anticoagulants. It appears that controlling severe lupus activity without increasing the risk of life-threatening complications remains an important goal in the treatment of SLE.

KEY WORDS: Systemic lupus erythematosus, Mortality, Infection, Anticoagulants, Jamaica


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