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© 1991 British Society for Rheumatology

brief-report

ARTICULAR DISEASE SEVERITY IN RHEUMATOID SUBJECTS WITH AND WITHOUT FELTY'S SYNDROME

M. J. McMAHON, S. HOLLIS*, P. A. SANDERS and D. M. GRENNAN

*University of Manchester Computational and Statistics Unit Hope Hospital, Salford M6 8HD
Rheumatic Diseases Centre Hope Hospital, Salford M6 8HD

Correspondence to: Correspondence to Dr D. Grennan.

Articular disease severity as measured by a radiographic score of hands and feet was compared in rheumatoid subjects with (21) and without (170) Felty's syndrome. Disease duration was a major determinant of joint destruction. When this was taken into consideration radiographic scores were no higher in the Felty's group than in rheumatoid subjects without Felty's syndrome. Immunogenetic associations previously described in Felty's syndrome are unlikely therefore to represent non—specific markers of disease severity and more likely to represent markers of extra—articular disease.

KEY WORDS: Radiological scoring, Felty—s syndrome


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