Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by MELICONI, R.
Right arrow Articles by FACCHINI, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by MELICONI, R.
Right arrow Articles by FACCHINI, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1992 British Society for Rheumatology

brief-report

T-CELL RECEPTOR GAMMA-DELTA POSITIVE LYMPHOCYTES IN SYNOVIAL MEMBRANE

R. MELICONI1,2,, M. UGUCCIONI3, A. D'ERRICO4, A. CASSISA4, L. FRIZZIERO5 and A. FACCHINI3

1Patologia Medica I, University of Bologna London
2Rheumatology Unit, Department of Medicine, UMDS, Guy's Hospital London
3Laboratorio di lmmunologia e Genetics, Istituto di Ricerca Codivilla Putti Bologna
4Istituto di Anatomia Patologica, University of Bologna U.S.L. 27, Bologna, Italy
5Unità di Reumatologia U.S.L. 27, Bologna, Italy

Correspondence to: Correspondence to Dr R. Meliconi, I Patologia Medica, Policlinico S. Orsola, Via Massarenti 9, 40138 Bologna, Italy

The distribution of T-lymphocytes expressing CD3 and T-cell receptor gamma-delta (T{gamma}/{delta}) has been examined by immunocytochemistry in the synovial membrane of eight patients with inflammatory arthritis (six rheumatoid arthritis, two spondyloarthritis) and eight with non-inflammatory arthritis (four osteoarthritis, four post-traumatic arthritis). T{gamma}/{delta} cells were present in eight out of eight inflammatory arthritis synovial membranes, but in only one out of eight noninflammatory membranes (P<0.005). The mean T{gamma}/{delta} percentage (of total T-cells) in inflammatory arthritis was 14% (range 7–25%). T{gamma}/{delta} cells were found mainly in the transitional area of the synovial membrane with a scattered distribution as single cells or couplets. No relation was found between the presence and percentage of T{gamma}/{delta} cells and disease duration or steroid treatment.

KEY WORDS: Rheumatoid arthritis, Inflammatory arthritis, Degenerative joint disease, Synovium, Lymphocytes


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.