© 1992 British Society for Rheumatology
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INTEGRIN EXPRESSION BY HUMAN ARTICULAR CHONDROCYTES
Department of Pathology, University of Edinburgh Medical School Teviot Place, Edinburgh EH8 9AG
Correspondence to:
Correspondence to Dr D. Salter
Expression of integrins, a family of cell adhesion proteins, by human articular cartilage chondrocytes in vivo has been studied by immunohistological techniques using cryostat sections and a panel of anti-integrin monoclonal antibodies. Chondrocytes strongly expressed ß1 and 
5 integrin subunits, known to form the classical fibronectin receptor, VLA-5, strongly. 1 was expressed more weakly and variably; 3 was expressed by occasional cells only. Chondrocytes did not express ß2, ß3 or other integrin subunits tested.
KEY WORDS: Cartilage, Immunohistology, Monoclonal antibodies, Cell ahesion molecules
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