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© 1992 British Society for Rheumatology

other

SEPTIC BONE, JOINT AND MUSCLE LESIONS ASSOCIATED WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION

R. A. HUGHES, I. F. ROWE, D. SHANSON* and C. S. KEAT

Departments of Rheumatology, Westminster Hospital 17 Page Street, London SWIP2AP
*Departments of Microbiology, Westminster Hospital 17 Page Street, London SWIP2AP

Ten episodes of musculoskeletal sepsis have been seen in nine patients with HIV infection. Seven patients had AIDS, circulating CD4-positive lymphocyte counts being less than 0.1 x 109/l in six. Septic arthritis recurred in seven patients, osteomyelitis in three and pyomyositis and bursitis each occurred in one patient. Staphylococcus aureus was isolated from four patients, atypical micro-organisms being found in three. Presentation of musculoskeletal infection in this patient group may be atypical but rapid diagnosis is important as early antimicrobial therapy is often successful.

KEY WORDS: HIV infection, Musculoskeletal sepsis, Septic arthritis, Osteomyelitis


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