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© 1992 British Society for Rheumatology


other

GASTROINTESTINAL ACCUMULATION OF INDIUM-111 LABELLED GRANULOCYTES IN REACTIVE ARTHRITIS

J. M. BEIER, L. ANDERSEN, T. M. HANSEN and P. B. FREDERIKSEN

Department of Rheumatology, Odense University Hospital 5000 Odense, Denmark
Department of Rheumatology, Kong Christian den X's Gigthospital 6300 Graasten, Denmark
Department of Nuclear Medicine, Odense University Hospital 5000 Odense, Denmark

Correspondence to: Correspondence to Jannie Manon Beier, Stove Klaus 30, 5270 Odense N, Denmark

Six patients with reactive arthritis (ReA) were examined for gastrointestinal accumulation of Indium-111 labelled granulocytes. Abnormal scintigrams were found in three of six patients all of which showed early (>4 h) accumulation of indium-111 labelled granulocytes which may represent small intestinal inflammation. Our findings may indicate that the small intestine is involved in ReA, and that indium-111 granulocyte scintigraphy is a useful method for demonstrating inflammatory changes in the small intestine in reactive arthritis (ReA).

KEY WORDS: Reactive arthritis, Indium-111 granulocyte scintigraphy, Gastrointestinal lesions, Non-steroidal anti-inflammatory drugs


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