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© 1993 British Society for Rheumatology

research-article

FEATURES OF SYSTEMIC SCLEROSIS (SCLERODERMA) IN AN IDENTICAL TWIN PAIR

N. J. COOK*, A. J. SILMAN{dagger},, J. PROPERT{ddagger} and M. I. D. CAWLEY*

*Rheumatology Unit, Southampton University Hospitals
{dagger}ARC Epidemiology Research Unit Manchester, Droitwich
{ddagger}Department of Rheumatology, Highfield Hospital Droitwich

Correspondence to: Correspondence to A. J. Silman, ARC Epidemiology Research Unit, Oxford Road, Manchester M13 9PT

The aetiology of systemic sclerosis (scleroderma) is unknown but it is thought to have both genetic and environmental components. The familial incidence of the disease is very low and we have been able to find only one report of scleroderma in identical twins which was in the Russian literature.

We report here on a set of identical twins and their mother who all had features of systemic sclerosis.

KEY WORDS: Scleroderma, Twins, Genetic, Environment


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