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© 1993 British Society for Rheumatology

other

AMYLOID ARTHRITIS ASSOCIATED WITH IgM KAPPA LYMPHOPLASMACYTOID LYMPHOMA

D.L. SCOTT, S. DONNELLY*, J. T. BOURNE{dagger}, D. A. LEVISON{ddagger}, D. V. DOYLE* and A. HAMMOND§

*Department of Rheumatology, Whipps Cross Hospital, Leytonstone London Ell 1NR
{dagger}Department of Rheumatology, Chesterfield and North Derby Royal Hospital Chesterfield S44 5BL, Derbyshire
{ddagger}Department of Pathology, Department of Histopathology, United Medical and Dental Schools Guy's Campus, London SE1 9RT
§The Maidslone Hospital General Wing, Hermitage Lane, Maidstone Kent ME16 9QQ

Amyloid arthritis is an uncommon cause of locomotor disease and may closely resemble RA. Macroglobinaemia is rarely associated with amyloidosis and there has been only one report of amyloid arthritis in this setting, the patient having had Waldenstrom's macroglobulinaemia. We report the occurrence of amyloid joint disease in the course of an IgM kappa B-cell dyscrasia which evolved over 16 years to an overt lymphoplasmacytoid lymphoma.

KEY WORDS: Amyloid, Macroglobulinaemia, Rheumatoid arthritis


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