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© 1993 British Society for Rheumatology


research-article

PRIMARY GENERALIZED OSTEOARTHRITIS AND BONE MASS

L. D. HORDON*,, S. P. STEWART{dagger}, P. R. TROUGHTON*, V. WRIGHT*, A. HORSMAN{ddagger} and M. A. SMITH{dagger}

*Rheumatology and Rehabilitation Research Unit Department of Clinical Medicine, University of Leeds
{dagger}Centre for Bone and Body Composition Research, Department of Clinical Medicine, University of Leeds
{ddagger}Department of Applied Biology, University of Hull

Correspondence to: Correspondence to L. D. Hordon, Rheumatology and Rehabilitation Research Unit, 36 Clarendon Road, Leeds LS2 9NZ

The association of OA with increased bone mass is controversial. This study measured BMD at the hip and spine and total body bone mineral (TBBM) by dual energy X-ray absorptiometry, and BMD at the distal forearm by single photon absorptiometry in 20 post-menopausal women with primary generalized OA. The data were compared with those from 89 normal controls. Osteoarthritic women had significantly increased BMD at the spine (P<0.001), distal forearm (P<0.05) and increased TBBM (P<0.01), but no difference was seen at the femoral neck. These differences were not explained by obesity. The influence of mobility is discussed.

KEY WORDS: Dual energy X-ray absorptiometry, Single photon absorptiometry, Spine, Distal forearm, Femoral neck


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