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© 1993 British Society for Rheumatology

research-article

EXTRA-ARTICULAR MANIFESTATIONS ARE UNCOMMON IN SOUTHERN CHINESE WITH RHEUMATOID ARTHRITIS

M. G. COHEN*,, E. K. LI{dagger}, P. Y. NG* and K. L. CHAN{dagger}

*Department of Rheumatology, Princess Alexandra Hospital Brisbane Queensland, Australia
{dagger}Department of Medicine, Prince of Wales Hospital and Chinese University of Hong Kong Shatin, NT, Hong Kong

Correspondence to: Correspondence to M. G. Cohen, 7 Kalang Ave, Killara, Sydney, NSW 2071, Australia

Rheumatoid arthritis is characterized by both articular and extra-articular manifestations. Few studies have addressed the prevalence of extra-articular manifestations in non-Caucasoid races. We have studied 153 Southern Chinese patients with RA and found that such features are uncommon when compared with previous reports in Caucasoids. The only extra-articular manifestations were rheumatoid nodules which were present in 4.6%, and episcleritis and cutaneous vasculitis in 0.7% each. A further 12.4% had mild sicca symptoms. These findings were in direct contrast with the severity of articular disease as 73% of patients had erosive disease which was graded as severe in 37%. The reason for the low prevalence of extra-articular manifestations is not known but may be due, in part, to the rarity of the HLA-DR4 subtype, HLA-Dw4 in the Southern Chinese population.

KEY WORDS: Nodules, Severity, Race


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