© 1993 British Society for Rheumatology
case-report |
POLYAUTOIMMUNITY IN A YOUNG WOMAN
Departments of Rheumatology, The Edith Cavell Hospital Bretton Gate, Peterborough PE3 6GZ
Correspondence to:
Correspondence to N. J. Sheehan
A young woman with the HLA phenotype A1, A2, B5, B8, DR3, DR4 developed RA, idiopathic thrombocytopenic purpura (ITP), pernicious anaemia (PA), Hashimoto's thyroiditis (HT), systemic sclerosis (SS), pancreatic exocrine insufficiency (PEI) and coeliac disease (CD) before dying from vasculitic complications. A family study revealed RA, PA and insulin-dependent diabetes mellitus (IDDM) amongst her first degree relatives. Her case emphasizes the clinical and immunogenetic links between the autoimmune diseases.
KEY WORDS: Autoimmunity, Rheumatoid arthritis, Idiopathic thrombocytopenic purpura, Pernicious anaemia, Hashimoto's thyroiditis, Systemic sclerosis, Pancreatic exocrine insufficiency, Coeliac disease, Insulin-dependent diabetes mellitus
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