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© 1993 British Society for Rheumatology

Non-Steroidal Anti-Inflammatory Drugs

P. R. Blower

SmithKline Beecham Pharmaceuticals Brentford, Middlesex TW8 9ET


  Abstract

Pre-clinical studies suggest that, whilst NSAIDs have similar anti-inflammatory efficacy, the potential for producing side effects varies widely between members of this class of therapeutic agents. The ways in which NSAIDs produce one of their most serious side effects, gastrointestinal damage, are outlined and consideration is given to ways of minimizing such problems.

KEY WORDS: NSAIDs, Efficacy, Side effects, Theraoeutic ratio, Gastrointestinal damage, Comparative studies


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