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© 1994 British Society for Rheumatology

case-report

ADENOCARCINOMA OF THE COLON AND ASSOCIATED NECROTIZING VASCULITTS OF MESENTERIC ARTERIES

P. T. CHAPMAN*, L. A. HUNTER{dagger} and J. L. O'DONNELL{ddagger}

*Departments of Rheumatology, Christchurch Hospital Christchurch, New Zealand
{dagger}Department of Pathology, Christchurch Hospital Christchurch, New Zealand
{ddagger}Department of Immunology, Christchurch Hospital Christchurch, New Zealand

Correspondence to: J. L. O'Donnell, Immunology Department, Christchurch Hospital, P O Box 4710, Christchurch, New Zealand.

Vasculitis associated with malignancy is uncommon, with the most well-known association being that between hairy cell leukaemia and polyarteritis nodosa. The less common association of vasculitis and solid tumours usually involves a cutaneous leukocytoclastic vasculitis. We report a patient with Duke's C adenocarcinoma of the sigmoid colon with associated necrotizing vasculitis of the mesenteric arteries and postulate that local factors may predominate in its pathogenesis.

KEY WORDS: Adenocarcinoma, colon, necrotizing vasculitis


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