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© 1995 British Society for Rheumatology

research-article

sIL-2R LEVELS IN RHEUMATOID ARTHRITIS: POOR CORRELATION WITH CLINICAL ACTIVITY IS DUE IN PART TO DISEASE DURATION

J. G. TEBIB*,, M. C. LETROUBLON{dagger}, E. NOEL*, J. BIENVENU{dagger} and M. BOUVIER*

*Service de Rhumatologie 69310 Pierre Bénite, France
{dagger}Laboratoiré d'Immunologie du Centre Hospitalier Lyon Sud 69310 Pierre Bénite, France

Correspondence to: Correspondence to: J. G. Tebib.

The serum levels of soluble interleulcin-2 receptors (sIL-2R) were measured in an attempt to determine whether they correlated with ‘disease activity’ in 59 patients suffering from rheumatoid arthritis. Our results indicate that serum levels of sIL-2R do not permit patients to be classified as having active or inactive disease according to standard clinical indices. A correlation between sIL-2R and disease duration could offer one explanation for the current discrepancies found in the literature.

KEY WORDS: Rheumatoid arthritis, Disease activity, sIL-2R


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