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© 1995 British Society for Rheumatology

case-report

SULPHASALAZINE-INDUCED LUPUS IN PSORIATIC ARTHRITIS

D. J. VEALE, M. HO and K. D. MORLEY

Department of Rheumatology, Ninewells Hospital and Medical School Dundee DD1 9SY

Correspondence to: Correspondence to: D. J. Veale.

Lupus syndromes have been described in rheumatoid arthritis and inflammatory bowel diseases treated with sulphasalazine. We describe two cases of lupus with clinical and serological disease, developing in seronegative, immunologically nude psoriatic arthritis following sulphasalazine treatment. On cessation of sulphasalazine the clinical and serologic features of lupus disappeared. This suggests that the lupus syndrome was induced by sulphasalazine rather than unmasked by it.

KEY WORDS: Sulphasalazine, Lupus, Psoriatic arthritis


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