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© 1995 British Society for Rheumatology


research-article

BEHÇET'S DISEASE IN INDIA: A CLINICAL, IMMUNOLOGICAL, IMMUNOGENETIC AND OUTCOME STUDY

I. PANDE*,, S. S. UPPAL, S. KAILASH{dagger}, A. KUMAR and A. N. MALAVTYA{ddagger}

Clinical Immunology and Rheumatology Division, Department of Medicine New Delhi-110029, India
{dagger}Computer Facility, All India Institute of Medical Sciences New Delhi-110029, India

Correspondence to: Correspondence to: I. Pande, Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, Bath, BA1 1RL.

The clinical and laboratory profile of 58 consecutive patients satisfying the ISG 1990 criteria for the diagnosis of Behçet's disease was analysed. It appears that Behçet's disease in India is predominantly ‘mucocutaneous’ and ‘arthritic’; ‘ocular’ and ‘neuro’ Behçet's being uncommon. In comparison to published literature, the onset of disease in this part of the world is significantly delayed. The pathergy test is rarely positive. There is no significant difference in clinical presentation and laboratory investigations between children and adults with this disease; also, no sex difference was observed. A combination of oral steroids and colchicine gives good relief in most cases. Preliminary observations seem to reflect no definite association of any known class I antigen to disease in this part of the world. A detailed study on immunogenetics is underway.

KEY WORDS: Behçet's disease, India

*Present address: Royal National Hospital for Rheumatic Diseases, Bath, BA1 1RL

{ddagger}Present address: Department of Medicine, Faculty of Medicine, Kuwait University, PO Box 24923, Safat, Kuwait 13110.


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