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© 1996 British Society for Rheumatology

review-article

ULTRAVIOLET IRRADIATION IN SYSTEMIC LUPUS ERYTHEMATOSUS: FRIEND OR FOE?

M. R. COHEN and D. A. ISENBERG

Bloomsbury Rheumatology Unit/Division of Rheumatology, Department of Medicine, University College London

Correspondence to: Correspondence to: D. A. Isenberg, Bloomsbury Rheumatology Unit, Arthur Stanley House, 40–50 Tottenham Street, London W1P 9PG

The long established notion that UV irradiation is always harmful to patients with systemic lupus erythematosus has been challenged by some recent reports of benefit using a form of phototherapy with UV-A1. In the review we discuss the different types of UV radiation, the links between certain forms of such radiation and clinical manifestations and consider the mechanisms involved

KEY WORDS: Systemic lupus erythematosus, Photosensitivity, Ultraviolet radiation, UV-A, UV-B


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