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© 1996 British Society for Rheumatology

other

‘SERONEGATTVE’ SJÖGREN'S SYNDROME MANIFESTED AS A SUBSET OF CHRONIC FATIGUE SYNDROME

M. NISHIKAI, K. AKIYA, T. TOJO, N. ONODA*, M. TANI{dagger} and K. SHIMIZU{dagger}

*Department of Pathology, Second Tokyo National Hospital Tokyo, Japan
{dagger}Department of Ophthalmology, Second Tokyo National Hospital Tokyo, Japan
Department of Internal Medicine and Clinical Research Institute, Second Tokyo National Hospital Tokyo, Japan

Correspondence to: Correspondence to: M. Nishikai, Department of Internal Medicine, Second Tokyo National Hospital, 2–5–1 Higashigaoka, Meguro-ku, Tokyo 152, Japan.

We determined the extent to which chronic fatigue syndrome (CFS) patients with sicca symptoms fulfil the diagnostic criteria for Sjögren’s syndrome (SS). Three sets of diagnostic criteria for SS, formulated by the Japanese, Europeans and Fox, were used. One-third of the CFS patients with sicca symptoms fulfilled the diagnostic criteria for SS. However, they were ‘seronegative’, differing from the ordinary primary SS.

KEY WORDS: Chronic fatigue syndrome, Sjogren's syndrome, Anti-La (SSB) antibodies, Anti-Ro (SSA) antibodies


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