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© 1996 British Society for Rheumatology

case-report

POLYARTERITIS NODOSA IN HUMAN IMMUNODEFICIENCY VIRUS INFECTION: REPORT OF FOUR CASES AND REVIEW OF THE LITERATURE

C. FONT, O. MIRÓ, E. PEDROL, F. MASANÉS, B. COLL-VINENT, J. CASADEMONT, M. C. CID and J. M. GRAU

Grup d' Investigació Muscular, Servei de Medicina Interna General, Hospital Clinic i Provincial, Universitat de Barcelona Barcelona, Spain

Correspondence to: Correspondence to: J. M. Grau, Grup d'Investigació Muscular, Servei de Medicina Interna General, Hospital Clinic i Provincial, Villarroel 170, 08036 Barcelona, Spain.

Four patients with HIV infection were diagnosed as having panarteritis nodosa type vasculitis in muscle samples taken by biopsy. Fever, weight loss and neuromuscular symptoms were the major complaints. All but one were successfully treated with a low dose of prednisone. The other patient refused treatment, but her muscular complaints did not worsen during 9 months of follow-up. Previously reported cases in the literature are reviewed

KEY WORDS: AIDS, HIV, Necrotizing arteritis, Rheumatic manifestations, Vasculitis, Panarteritis nodosa, Prednisone, Neuromuscular symptoms, Muscle biopsy, Muscle atrophy


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