The British Journal of Rheumatology, Vol 37, 539-543, Copyright © 1998 by British Society for Rheumatology
T Jones and MW Davie
Forearm bone mineral density (BMD) was investigated in women to identify
osteoporosis at the spine or femoral neck (or both) defined by WHO criteria
(T score -2.5) without requirement for fracture. BMD was measured by
single-energy X-ray absorptiometry (DTX100) and by dual- energy X-ray
absorptiometry (DXA) in the lumbar spine and femoral neck in 422 subjects
aged 22-90 yr. A total of 62% of subjects with osteoporosis (at the spine,
femoral neck, or both sites) were detected with 89% specificity [receiver
operating characteristics (ROC) analysis] and included all subjects below
forearm BMD 0.34 g/cm2. Conversely, above 0.419 g/cm2, only 10% of patients
had osteoporosis. A total of 71.8% of women could be assigned either to
those who warranted therapy (<0.34 g/cm2) or to those who did not
(>0.419 g/cm2) with 90% certainty. Subjects with forearm BMD between
0.34 and 0.419 g/cm2, who constituted 28.2% of the total group and included
31% of subjects with osteoporosis, had a 40% chance of having osteoporosis.
This leads to a high identification rate on subsequent DXA scanning, which
is thus used efficiently.
ORIGINAL PAPERS
Bone mineral density at distal forearm can identify patients with osteoporosis at spine or femoral neck
Charles Salt Research Centre, Robert Jones and Agnes Hunt Hospital, Oswestry, Shropshire.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  M. Worsfold, D. E. Powell, T. J.W. Jones, and M. W.J. Davie Assessment of Urinary Bone Markers for Monitoring Treatment of Osteoporosis Clin. Chem., December 1, 2004; 50(12): 2263 - 2270. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P J Ryan Bone densitometry in the management of Colles' fractures: which site to measure? Br. J. Radiol., December 1, 2001; 74(888): 1137 - 1141. [Abstract] [Full Text] [PDF]
|
|