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Rheumatology, Vol 38, 39-46, Copyright © 1999 by British Society for Rheumatology

ORIGINAL PAPERS

Economic comparison of nimesulide and diclofenac, and the incidence of adverse events in the treatment of rheumatic disease in Greece

L Liaropoulos
Centre for Health Services Management and Evaluation, University of Athens, Faculty of Nursing, Greece.

In Greece a 15-day treatment of rheumatic disease with diclofenac costs 56% more than treatment with nimesulide. This is due to the lower incidence of gastrointestinal adverse events with nimesulide, and the absence of serious gastrointestinal complications leading to hospitalization, which more than offset the higher acquisition cost of nimesulide. The average saving by using nimesulide instead of diclofenac is about US$21 per patient for a 15-day treatment period.
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