Rheumatology Advance Access originally published online on March 23, 2004
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Rheumatology 2004; 43: 758-764
Rheumatology Vol. 43 No. 6 © British Society for Rheumatology 2004; all rights reserved
Clinical |
Measurement of fatigue and discomfort in primary Sjögren's syndrome using a new questionnaire tool
University of Birmingham, Rheumatology Department, Birmingham, 1 University of Birmingham, School of Psychology, Birmingham, UK.
Correspondence to: S. J. Bowman, Rheumatology Department, University Hospital Birmingham (Selly Oak), Raddlebarn Road, Birmingham B29 6JD. E-mail: s.j.bowman{at}bham.ac.uk.
Objective. Fatigue is a prominent symptom in primary Sjögren's syndrome (PSS). We set out to compare existing instruments and a new tool for measuring fatigue and general discomfort in PSS, with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and healthy controls.
Methods. Groups of female Caucasian PSS patients completed a new questionnaire developed from PSS patients’ own vocabulary, as well as the SF-36, WHOQOL-BREF and HAD scales. For comparison, the questionnaire was also completed by groups of SLE and RA patients and healthy controls.
Results. Each disease group differed significantly from healthy controls on each facet of fatigue and general discomfort in the new tool. Somatic fatigue was worst in RA, while mental fatigue was worst in PSS and SLE. The facets of somatic fatigue and discomfort in the new tool correlated well with comparable domains in existing scales.
Conclusions. Fatigue in PSS can be measured using this new Sjögren's-based psychometric instrument. The new questionnaire tool was more sensitive than the SF-36, WHOQOL-BREF and HAD at distinguishing the three rheumatic disorders from controls.
KEY WORDS: Primary Sjögren's syndrome, Questionnaire tools, Fatigue and discomfort.
*The UK Sjögren's Interest Group includes: Deva Situnayake MD, FRCP, Caroline Gordon MD, FRCP, Liviu Hanu-Cernat MBBS, FDSRCS, Stephanie Heaton RGN and Bernard Speculand FDS, FRACDS, City Hospital, Birmingham, UK; John Ainsworth FRCOphth, Ahmed Bawendi MSc, MD and Georgina Holmes RGN, Birmingham Heartlands & Solihull Hospitals, Birmingham, UK; John Hamburger FDS, FRCPath, School of Dentistry, Birmingham, UK; Peter Maddison MD, FRCP, Bangor, Wales, UK; Diarmuid Mulherin MD, MRCP, Cannock Chase Hospital, Staffordshire, UK; Pepe Shirlaw BDS, FDSRCPS, UMDS, London, UK; Michael Snaith MD, FRCP, Mohammed Akil MD, FRCP and Christine Yeoman PhD, FDSRCS, Royal Hallamshire Hospital, Sheffield, UK; Anne Field DDSci, FDSRCS, Jocelyn Rostron BDS, FDSRCS, Luke Dawson PhD and Leslie Longman PhD, FDSRCS, Liverpool Dental Hospital, Liverpool, UK; Ian Griffiths BSc, FRCP and Brian Davidson MD, MRCP, Freeman Hospital, Newcastle, UK; Neil McHugh MD, FRCP and Ms Nicola Waldron RGN, Royal National Hospital, Bath, UK; Colin Pease MD, FRCP and Elizabeth Tyas RGN, Leeds General Infirmary, Leeds, UK; Elizabeth Price MD, FRCP, Princess Margaret Hospital, Swindon, UK; David Isenberg MD, FRCP, Maria-Jose Leandro MD and Nurhan Sutcliffe MD, MRCP, Middlesex Hospital London, UK.
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