Rheumatology Advance Access originally published online on July 19, 2005
Rheumatology 2005 44(11):1422-1427; doi:10.1093/rheumatology/kei032
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A randomized clinical trial of an individualized home-based exercise programme for women with fibromyalgia
1 Division of Clinical Epidemiology, McGill University Health Centre, 2 Department of Medicine and 3 Department of Epidemiology and Biostatistics, McGill University and 4 Department of Rheumatology, McGill University Health Centre, Montreal, Canada.
Correspondence to: D. Da Costa, Division of Clinical Epidemiology, McGill University Health Centre, 1650 Cedar Ave., Montreal, Quebec, H3G 1A4 Canada. E-mail: Deborah.DaCosta{at}mcgill.ca
Objective. To determine the efficacy of a 12-week individualized home-based exercise programme on physical functioning, pain severity and psychological distress for women with fibromyalgia (FM).
Methods. Seventy-nine women with a primary diagnosis of FM were randomized to a 12-week individualized home-based moderate-intensity exercise programme or to a usual care control group. Outcomes were functional capacity (Fibromyalgia Impact Questionnaire), pain severity and psychological distress. Outcomes were measured at study entry, at the end of the 12-week intervention, and at 3 and 9 months following completion of the intervention.
Results. On the basis of intention-to-treat analyses, a significant improvement in functional capacity at 3 and 9 months following treatment for participants in the exercise group who were more functionally disabled at study entry was observed. At both 3 and 9 months post-treatment, the mean estimated benefit of the intervention was more than 10 points [–12.3 (95% CI, –21.9 to –2.8); –10.8 (95% CI, –21.5 to –0.2)]. Compared with the control group, statistically significant improvements in upper body pain were evident in the exercise group at post-treatment. These between-group differences in upper body pain were maintained at 3 and 9 months post-treatment. No statistically significant group differences on lower body pain and psychological distress were found.
Conclusions. Home-based exercise, a relatively low-cost treatment modality, has the potential to improve important health outcomes in FM.
KEY WORDS: Fibromyalgia, Home-based exercise, Randomized controlled trial
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