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Rheumatology 2009 48(1):83-87; doi:10.1093/rheumatology/ken427
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Risk factors for the development of hip osteoarthritis: a population-based prospective study

R. Juhakoski1, M. Heliövaara2, O. Impivaara2, H. Kröger3, P. Knekt2, H. Lauren4 and J. P. A. Arokoski5

1Department of Physical and Rehabilitation Medicine, Mikkeli Central Hospital, Mikkeli, 2Department of Health and Functional Capacity, National Public Health Institute, Helsinki and Turku, 3Department of Orthopaedics, Traumatology and Hand Surgery, Kuopio University Hospital, Kuopio, 4Helsinki Medical Imaging Center, Helsinki and 5Department of Physical and Rehabilitation Medicine, Kuopio University Hospital and Institute of Clinical Medicine, University of Kuopio, Kuopio, Finland.

Correspondence to: R. Juhakoski, Department of Physical and Rehabilitation Medicine, Mikkeli Central Hospital, Porrassalmenkatu 35–37, FIN-50100 Mikkeli, Finland. E-mail: riikka.juhakoski{at}esshp.fi


  Abstract

Objectives. Potential risk factors and their roles in the aetiology of hip OA are poorly understood. We analysed several alleged risk factors predisposing to hip OA in a 22-yr prospective study.

Methods. A comprehensive health survey was carried out in 1978–80 in a nationally representative sample of adult Finns. In 2000–01, 1286 participants in that survey were invited for re-examination, and 909 agreed to participate. After excluding those with hip OA at the baseline and those who were no longer working, a total of 840 subjects constituted the present study population. Hip OA was diagnosed on the basis of a standardized clinical examination by physicians who applied uniform criteria both at the baseline and at the re-examination phase.

Results. After 22 yrs of follow-up, hip OA was diagnosed in 41 subjects (4.9%). Heavy manual labour predicted the risk of developing hip OA [adjusted odds ratio (OR) 6.7; 95% CI 2.3, 19.5]. Permanent damage as a consequence of any musculoskeletal injury was also an independent predictor of hip OA (adjusted OR 5.0; 95% CI 1.9, 13.3). BMI, smoking, alcohol intake and leisure time physical activity were not factors which were predictive for hip OA.

Conclusion. Heavy physical stress at work and major musculoskeletal injuries are associated with an increased risk of developing clinically diagnosed hip OA.

KEY WORDS: Osteoarthritis, Hip joint, Risk factors

Submitted 13 May 2008; revised version accepted 7 October 2008.
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