Lymphocyte Response to Enterobacterial Biostructures in Seronegative Spondarthritis: Specific T-Cell Mediated Immunity or Non-Specific Polyclonal B-Cell Activation?
Correspondence to Dr. Gross. Immunology Laboratories. I Med Um-klinik. Schittenhelmstrasse 12. 2300 Kiel 1. W. Germany
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The proliferative response, as measured by thymidine uptake and the B-cell differentiation response, as measured by Ig secretion, have been studied in peripheral blood mononuclear cells obtained from patients with ankylosing spondylitis, Yersima reactive arthritis, Klebsiella infections and healthy controls, following stimulation with enterobacterial biostructures
KEY WORDS: Enterobacteria, Klebsiellapneumoniae, Polyclonal B-cell activation