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Rheumatology 2000; 39: 1424-1425
© 2000 British Society for Rheumatology

Letters to the Editor

Lack of evidence for an association between hantavirus infections and Wegener's granulomatosis, microscopic polyangiitis, Churg–Strauss syndrome and giant cell arteritis

P. Gerke, D. Wichmann1, U. Schönermarck4, M. Schütt, H. Feldmann2, T. G. Ksiazek3, P.-M. Rob and W. L. Gross4

Department of Medicine I, Medical University of Lübeck,
1 Institute of Medical Virology, University of Marburg, Germany,
2 Canadian Science Centre for Human and Animal Health, Health Canada, Winnipeg, Alberta, Canada,
3 Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA and
4 Department of Rheumatology, Medical University of Lübeck and Rheumaklinik Bad Bramstedt, Germany

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SIR, Systemic vasculitides are a heterogeneous group of disorders characterized by inflammation of vessel walls. Much progress has been made in understanding their pathophysiology and pathogenesis, but the cause remains unclear in the majority of the cases. Associations with distinct viral infections have been demonstrated [1]. Among agents that have been implicated are hantaviruses, the infectious causes of haemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome [2]. HFRS occurs worldwide and may be clinically inapparent. Hantaviruses are known to infect . . . [Full Text of this Article]


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