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Rheumatology 2000; 39: 213-215
© 2000 British Society for Rheumatology

Letters to the Editor

Psoriasis and diffuse systemic sclerosis: a report of three patients

B. Harrison3, A. Herrick and C. Griffiths1

University of Manchester Rheumatic Diseases Centre and
1 University of Manchester Section of Dermatology, Hope Hospital, Salford M6 8HD, UK

Sir, We report three patients who presented to the Rheumatic Diseases Centre, Hope Hospital, UK with the rare combination of diffuse systemic sclerosis (SSc) and psoriasis, one of whom also had psoriatic arthritis (PsA). In two of the patients there was a temporal relationship between the development of the two conditions, and in both these patients the SSc followed a very aggressive course with rapidly progressive skin involvement. The possible explanations for the co-existence of these two diseases are discussed.

Patient 1. A 54-yr-old female who initially presented to the Dermatology Service in 1993 with an acute onset of pustular psoriasis on the palms and soles. She was treated with the systemic retinoid acitretin. In March 1995 she was referred to the rheumatologists with an 8-month history of Raynaud's phenomenon and diffuse skin thickening over the upper limbs and trunk. On initial . . . [Full Text of this Article]

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