Skip Navigation

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (17)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Tak, P. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tak, P. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Rheumatology 2000; 39: 817-820
© 2000 British Society for Rheumatology

Editorial

Lessons learnt from the synovial tissue response to anti-rheumatic treatment

P. P. Tak

Division of Clinical Immunology and Rheumatology, Academic Medical Centre, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands

The first 150 words of the full text of this article appear below.

There has been increased interest in studies on synovial tissue in recent years. This can be explained by technical developments and by the recognition of the synovium as the primary site of inflammation in patients with rheumatoid arthritis (RA) and other arthritides. Obviously, examination of peripheral blood and synovial fluid may provide insight into the production of soluble mediators as well as the dynamics of migration of inflammatory cells into different compartments. However, it has become clear that such studies yield only indirect information about the events in the synovium. Hence, there has been an upsurge in investigations of the pathological changes taking place in the rheumatoid synovium [1]. These studies have been used to provide more insight into the pathogenesis and to identify features which might be used for diagnostic purposes and to provide a prognosis [2].

The relevance of examination of the synovium has . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Ann Rheum DisHome page
M D Smith, E Barg, H Weedon, V Papengelis, T Smeets, P P Tak, M Kraan, M Coleman, and M J Ahern
Microarchitecture and protective mechanisms in synovial tissue from clinically and arthroscopically normal knee joints
Ann Rheum Dis, April 1, 2003; 62(4): 303 - 307.
[Abstract] [Full Text] [PDF]

Home page
 Ann Rheum DisHome page
P P TAK
Analysis of synovial biopsy samples: opportunities and challenges
Ann Rheum Dis, December 1, 2000; 59(12): 929 - 930.
[Full Text]