Rheumatology 2000; 39: 1044-1046
© 2000 British Society for Rheumatology
Letters to the Editor |
Thymoma-associated systemic lupus erythematosus, exacerbating after thymectomy. A case report and review of the literature
Department of Internal Medicine and Rheumatology, University Hospital Maastricht, The Netherlands
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SIR, Myasthenia gravis (MG), pure red cell aplasia and acquired hypogammaglobulinaemia are well recognized to be associated with thymoma, but systemic lupus erythematosus (SLE) can also be a manifestation of thymoma. The literature on the features of thymoma-associated SLE and the effect of thymectomy on SLE disease activity is conflicting.
A 76-yr-old Caucasian woman presented with malaise and weight loss of 10 kg over the past 6 months. Clinical examination at that time revealed a low body weight of 46 kg and a body length of 160 cm. Laboratory examination showed
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