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Rheumatology 2001; 40: 939-940
© 2001 British Society for Rheumatology

Paediatric Rheumatology

A normal ECG at birth does not exclude significant congenital cardiac conduction disease associated with maternal anti-Ro antibodies

Paediatric Rheumatology/Series Editor: P. Woo

Letters to the Editor

P. A. Gordon, M. A. Khamashta, G. R. V. Hughes and E. Rosenthal1

The Lupus Unit, St Thomas Hospital, London and
1 Department of Paediatric Cardiology, Guy's Hospital, London, UK

SIR, Isolated congenital complete heart block (CCHB) is a rare complication of pregnancy, strongly associated with maternal anti-Ro/SSA antibody, which is found in up to 91% of cases [1].The damage occurs during fetal development, heart block generally first being detectable between 16 and 24 weeks of gestation. Only approximately 2% of pregnancies in women with the anti-Ro antibody are complicated by CCHB [2]. Even in women who have had children with CCHB the risk of recurrence is only 16% . . . [Full Text of this Article]

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