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Rheumatology 2001; 40: 1064-1065
© 2001 British Society for Rheumatology

Letters to the Editor

Successful treatment of hepatitis B-associated vasculitis using lamivudine as the sole therapeutic agent

A. Filer, A. Hughes1, K. Kane2, D. Mutimer1 and P. Jobanputra3

Department of Rheumatology, University of Birmingham,
1 Liver and Hepatobiliary Unit, Queen Elizabeth Hospital, Birmingham,
2 Department of Gastroenterology and
3 Department of Rheumatology, Selly Oak Hospital, Birmingham, UK

SIR, We read with interest the report by MacLachlan et al. [1] describing a patient with hepatitis B virus (HBV)-associated polyarteritis nodosa (PAN) treated with lamivudine and immunosuppression. Another recent report described the successful use of lamivudine and interferon alpha (IFN{alpha}) [2]. We report a patient with vasculitis associated with chronic HBV antigenaemia whose disease was successfully managed with lamivudine alone.

A 52-yr-old hospital porter was admitted to hospital in December 1998 with a 10-month history of intermittent, purpuric rash affecting his legs and buttocks. He had paraesthesiae of his legs with numbness of the left foot, intermittent polyarthritis, mild weight loss and an altered bowel . . . [Full Text of this Article]

Notes

References

D. Maclachlan, M. Battegay1, A. L. Jacob2 and A. Tyndall

University Department of Rheumatology, Felix Platter Spital, Burgfelder Strasse 101, CH-4055 Basel,
1University Medical Outpatient Department, Kantonsspital Basel, Petersgraben 4, Basel and
2University Institute of Diagnostic Radiology, Kantonsspital Basel, Petersgraben 4, Basel, Switzerland


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A. Filer, A. Hughes, K. Kane, D. Mutimer, P. Jobanputra, D. Maclachlan, M. Battegay, A. L. Jacob, and A. Tyndall
Successful treatment of hepatitis B-associated vasculitis using lamivudine as the sole therapeutic agent
Rheumatology, September 1, 2001; 40(9): 1064 - 1065.
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