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Rheumatology 2001; 40: 1066-1068
© 2001 British Society for Rheumatology

Letters to the Editor

Ocular involvement in Wegener's granulomatosis responding to intravenous cyclophosphamide

E. Cuende, A. Ruiz Mena1, J. Andonegui1, I. Minguela2 and J. C. Vesga

1 Rheumatology Unit, Ophthalmology Service and
2 Nephrology Service, Hospital Txagorritxu, Osakidetza, Vitoria, Spain

SIR, Wegener's granulomatosis (WG) is a systemic vasculitis of the upper and lower respiratory tracts together with glomerulonephritis. In addition, variable degrees of disseminated vasculitis, involving both small arteries and veins, may occur [1, 2]. Eye involvement is frequent and may range from a mild conjunctivitis to dacryocystitis, episcleritis, scleritis, granulomatous sclerouveitis, ciliary vessel vasculitis and retro-orbital mass lesions. Retinal vasculitis is described rarely [3]. Failure of antineutrophil cytoplasmic antibody (c-ANCA) titres to revert to normal levels may be associated with the potential for relapse in patients with ocular manifestations of Wegener's granulomatosis [4]. We present the . . . [Full Text of this Article]

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