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Rheumatology 2002; 41: 111-113
© 2002 British Society for Rheumatology

Letters to the Editor

Reversible selective ß2-adrenoceptor agonist-induced myopathy

J.-P. Hellier, M. Baudrimont1, J. C. Dussaule2 and F. Berenbaum

Department of Rheumatology,
1 Department of Pathology and
2 Department of Electrophysiology, Hôpital Saint-Antoine, 184, rue du fbg Saint-Antoine, 75012 Paris, France

SIR, Salbutamol and formoterol, two ß2-adrenergic agonists, are commonly prescribed in bronchospasm. Headache, shaking, palpitation and skin rash are the most common side-effects related to these compounds. Muscle cramps have also been reported but are usually mild and do not necessitate stoppage of the treatment. We report a patient with clinical, reversible ß2-adrenoceptor agonist myopathy. The myopathy was demonstrated electrically and histologically. He had received a well-documented high cumulative dose of ß2-adrenoceptor agonists, and in whom . . . [Full Text of this Article]

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