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Rheumatology 2002; 41: 1450-1452
© 2002 British Society for Rheumatology


Paediatric Rheumatology

Anti-tumour necrosis factor therapy associated with cutaneous vasculitis

P. A. Livermore and K. J. Murray

Paediatric Rheumatology Unit, Great Ormond St Hospital for Children, Great Ormond Street, London WC1N 3JH, UK

The first 10% of the full text of this article appears below.

SIR, We read with interest the letter by McCain et al. [1] and we wish to add our experience of a case of probable vasculitis or cutaneous reaction secondary to anti-tumour necrosis factor (anti-TNF) therapy, as has been noted by others. While injection site reactions can occur in up to 20% of patients receiving etanercept [2], more generalized reactions are only recently being recognized [1, 3–6].

We report a Caucasian girl who was referred to our rheumatology unit at 91/2; yr of age in October 1995 with a 6-month history of intermittent daily high-spiking fever, lethargy, evanescent rash accompanying the fever, and joint pain and stiffness. Clinical . . . [Full Text of this Article]


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