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Rheumatology 2002; 41: 228-229
© 2002 British Society for Rheumatology

Paediatric Rheumatology

Etanercept in four children with therapy-resistant systemic juvenile idiopathic arthritis

Paediatric Rheumatology/Series Editor: P. Woo

R. ten Cate1,3,, L. W. A. van Suijlekom-Smit3, D. M. C. Brinkman1, W. P. Bekkering2, C. J. A. Jansen-van Wijngaarden4 and J. M. Vossen1

Departments of
1 Paediatrics and
2 Physical Therapy, Leiden University Medical Centre and Departments of
3 Paediatrics and
4 Physical Therapy, University Hospital Rotterdam/Sophia's Children's Hospital, The Netherlands

Letter to the Editor

SIR, Systemic juvenile idiopathic arthritis (sJIA) is a difficult disease to treat. Drugs that can be effective, such as steroids and methotrexate (MTX), often lead to complications. Some patients are truly therapy-resistant, meaning that the combination of non-steroidal anti-inflammatory drugs (NSAIDs), steroids, MTX up to 1 mg/kg/week and cyclosporin A (CyA) (5 mg/kg/day) [1] fails to induce remission or . . . [Full Text of this Article]

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