Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Agarwal, V.
Right arrow Articles by Aggarwal, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Agarwal, V.
Right arrow Articles by Aggarwal, A.
Related Collections
Right arrow Juvenile Idiopathic Arthritis
Right arrow Immunology of Paediatric Rheumatic Disease
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Rheumatology 2002; 41: 466-467
© 2002 British Society for Rheumatology

Paediatric Rheumatology

Immune complexes contain immunoglobulin A rheumatoid factor in serum and synovial fluid of patients with polyarticular juvenile rheumatoid arthritis

Paediatric Rheumatology/Series Editor: P. Woo

V. Agarwal, R. Misra and A. Aggarwal

Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India

SIR, Immune complexes (IC) are believed to play a role in the pathogenesis of juvenile rheumatoid arthritis (JRA) [1]. Their prevalence varies from 39 to 79% depending on the method used for their detection [2]. Immunoglobulin M (IgM)- and IgG-containing IC activate the classical complement pathway, whereas IgA-containing IC activate an alternative complement pathway. Several groups, including ours, have shown complement activation through either or both pathways in patients with JRA [3, 4]. IgA rheumatoid factor (RF) has rarely been studied in . . . [Full Text of this Article]

Notes

References


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?