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Rheumatology 2002; 41: 588-589
© 2002 British Society for Rheumatology

Letters to the Editor

Wegener's granulomatosis and rheumatoid arthritis overlap

H. Chinoy and F. McKenna

Rheumatic Diseases Unit, Trafford General Hospital, Moorside Road, Urmston, Manchester M41 5SL, UK

SIR, Wegener's granulomatosis and rheumatoid arthritis (RA) are clinically and immunologically independent diseases. In both cases, treatment with immunosuppression is required for active disease. Associations have been described. Schwarz-Eywill et al. [1] report a case of RA that manifested generalized Wegener's granulomatosis despite treatment with methotrexate. A study by Mustila et al. [2] showed that in early RA, pANCA (antineutrophilic cytoplasmic antibodies, perinuclear pattern) was associated with serological markers of RA . . . [Full Text of this Article]

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