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Rheumatology 2002; 41: 721-724
© 2002 British Society for Rheumatology
Editorial |
The muscle in fibromyalgia
Rheumatology Unit, University Hospital, 581 85 Linköping, Sweden
| The first 150 words of the full text of this article appear below. |
The main symptoms in fibromyalgia are muscle pain, stiffness and muscle fatigue. In 1981, when we started our fibromyalgia studies, we had a lot of patients with such symptoms at our clinic. None of them had arthritis or laboratory signs of inflammation, which is the key that opens the door to the rheumatology unit. Fibromyalgia patients in our own studies were all diagnosed according to the Yunus criteria from 1981 to 1990 and according to the ACR criteria since 1990 [1, 2].
The first questions that should be asked are these: When do we feel pain in the muscles? What kind of changes in the muscle tissue produce pain? Is there any evidence that such changes exist in the muscle in fibromyalgia?
Muscle fibres are not provided with nociceptors [for reviews see 35]. Chronic degenerative muscle disorders are not painful. Inflammation can cause sensitization
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